77th ASSH Annual Meeting - Back to Basics: Practice and Education-IC24: Congenital Hand: Whats New in Treatment and Understanding in 2022 (AM22)

Video Transcription

Video Summary

In this video transcript, four speakers discuss various topics related to congenital hand anomalies. The first speaker talks about recent updates in the understanding and classification of congenital hand anomalies. They emphasize that the OMT classification system has been updated multiple times and now includes the reclassification of certain diagnoses such as cleft hand and arthrogryposis. The speaker also mentions the importance of genetics in understanding congenital anomalies. <br /><br />The second speaker discusses the use of registries for gaining a better understanding of congenital differences of the hand. They explain that administrative databases and condition-specific registries can provide valuable data, but there is a need for more comprehensive and patient-centered outcome measures. They introduce the Congenital Upper Limb Differences (CUD) registry as an example of a prospective cohort study that aims to assess the upper extremity function and health status of children with congenital hand differences. They highlight the importance of collecting reliable data and engaging in collaborative research efforts.<br /><br />The third speaker focuses on recent developments in the treatment of PIK3CA-related overgrowth spectrum disorders. They explain that these conditions are caused by mutations in the PIK3CA gene, which affects cell growth pathways. They discuss the use of pharmacologic treatments that target different parts of the PIK3CA pathway, such as mTOR inhibitors and PIK3CA inhibitors. They highlight the potential of these treatments in improving symptoms and reducing tissue overgrowth. <br /><br />The fourth speaker provides an update on the treatment of hypoplastic thumb and syndactyly. They discuss different surgical techniques, such as full thickness skin grafts for syndactyly release and opponent's plasties for thumb reconstruction. They also mention emerging techniques, such as the use of synthetic dermal substitutes and composite tissue transfers. They emphasize the importance of tailoring the treatment approach based on the specific type and severity of the anomaly.

Meta Tag

Session Tracks Pediatrics/Congenital

Speaker Ann E. Van Heest, MD

Speaker Charles A. Goldfarb, MD

Speaker Donald S. Bae, MD

Speaker Michelle A. James, MD

Keywords

congenital hand anomalies

OMT classification system

genetics

registries

upper extremity function

PIK3CA-related overgrowth spectrum disorders

pharmacologic treatments

surgical techniques

syndactyly